Single domain antibodies (sdAbs), also known as VHH antibodies or nanobodies™, are small antigen-binding fragments derived from camelids that have a single monomeric variable antibody domain. sdAbs ...
(A) Cryo-EM structure overview of HSV-1 gB in complex with D48 Fab. The side view and top view were presented. The HSV-1 gB trimer and D48 Fab VH/VL were colored differently. (B) Neutralization assay ...
The antibody therapeutics industry is growing at an incredible pace. From early monoclonal therapeutic antibodies to modern bispecific and multispecific antibodies, single domain antibodies (VHHs), ...
A promising new Small Methods study discusses the ability of shark-derived antibodies to protect against multiple variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well ...
In a recent article posted to the bioRxiv* preprint server, researchers identified an ultralong bovine antibody that neutralizes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe ...
While there are an increasing number of companies leveraging the capabilities of artificial intelligence (AI) in the pharmaceutical industry (Box 1), there are relatively few operations dedicated ...