Ribosome biogenesis and assembly constitute a fundamental cellular process, intricately coordinating the synthesis and maturation of ribosomal RNA with the assembly of ribosomal proteins. This tightly ...

Ribosomal subunit assembly and biogenesis constitute a fundamental process vital for cellular protein synthesis across all domains of life. This complex, multi-step pathway involves the transcription ...

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made. During brain development, neural ...

Schematic of ribosome biogenesis. Eukaryotic ribosome biogenesis involves RNA polymerases I/II/III (Pol I, Pol II, and Pol III), transcribing rDNA to rRNA, and producing 47S pre-rRNA in the nucleolus.

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making ...