DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells. Their functions include control of transcription and translation, DNA ...

Scientists have deciphered the structure of an essential part of Mediator, a complex molecular machine that plays a vital role in regulating the transcription of DNA. Scientists have deciphered the ...

Research scientists have managed to sequence DNA transcription initiation "image by image" to show how DNA is copied onto RNA. Some of the mechanisms of this crucial stage have now been revealed. Gene ...

Researchers have determined the structure of a molecular protein complex that helps DNA to be read and its instructions carried out. The complex, called TFIIIB, is of interest to cancer researchers ...

The foundations of life hinge on the precise replication and transcription of DNA and the translation of the resultant messenger RNAs. These processes are responsible for accurately passing down and ...

Transcription is the process by which DNA is converted into messenger RNA in preparation for translation into a functional product. Extrinsic agents, such as ionizing radiation or chemical mutagen and ...

Once transcription stops, the enzyme and the mRNA transcript disengage from the template DNA, which re-winds to form a double helix. The mRNA transcript or pre-mRNA is then released for ...