Chemotherapy for breast cancer - Mayo Clinic
Jan 10, 2025 · Gene expression profiling tests, such as Oncotype DX, EndoPredict and MammaPrint, may help predict the risk of recurrence and give your doctor an idea of how your cancer cells might …
TERT expression may better predict meningioma behavior
Oct 7, 2025 · Researchers co-led by a Mayo Clinic Neurosurgery chair have demonstrated that telomerase reverse transcriptase (TERT) gene expression in meningiomas predicts earlier disease …
Stem cell therapy for degenerative intervertebral disk disease: Q and A ...
Jun 23, 2017 · In collaboration with orthopedic and neurosurgery researchers, we are examining the epigenetics in identifying gene expression profiles associated with disk degeneration. The purpose of …
Genetic testing - Mayo Clinic
Apr 14, 2020 · Genetic testing: Learn why it's done, how to prepare and what to expect from diagnostic tests, carrier tests, prenatal tests and newborn screening.
mRNA transfection improves CTL response in immunotherapy
Apr 30, 2022 · Reduced NKG7 expression altered cytolytic granule number, trafficking and calcium release, resulting in decreased killing of tumor cells by CTLs. Transfection of CTLs with NKG7 …
Disease expression and familial transmission in Fuchs' endothelial ...
Jul 20, 2021 · For more information Xu TT, et al. Disease expression and familial transmission of Fuchs endothelial corneal dystrophy with and without CTG18.1 expansion. Investigative Ophthalmology & …
HER2-positive breast cancer: What is it? - Mayo Clinic
Apr 9, 2024 · HER2-positive breast cancer tends to be more aggressive than other types of breast cancer. Treatments that target HER2 are very effective.
Phase 1 clinical trial testing gene therapy treatment for knee ...
Oct 10, 2025 · Results demonstrate that injection of local gene therapy for knee joints is safe and achieves sustained, intra-articular concentrations of a therapeutic gene product.
Genomic testing expands options for melanoma staging
Nov 8, 2025 · A recent multicenter clinical trial based on research developed by Mayo Clinic experts provides valuable new insights into the management of early- and intermediate-stage cutaneous …
Mayo researchers prepare to launch clinical trial using gene therapy ...
Oct 26, 2016 · These emerging regenerative technologies, focusing on structural repair and functional restoration, are poised to provide innovative solutions that address unmet patient needs. In separate …