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AKT Signaling Pathway: Regulation by the Insulin Signaling Cascade
Lesson on the Insulin Signaling Pathway and its Regulation of the AKT Pathway. The insulin signaling cascade is activated upon binding of insulin to the insulin receptor. Afterwards, downstream targets, including IRS1/2, become activated, eventually leading to activation of AKT via two distinct mechanisms and two important phosphorylation sites ...
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